Department of Chemical and Environmental Engineering, University of California, Riverside, CA 92521, United States.
Curr Opin Biotechnol. 2009 Dec;20(6):659-67. doi: 10.1016/j.copbio.2009.09.013. Epub 2009 Oct 31.
In nature, both prokaryotes and eukaryotes have evolved a wide spectrum of pathways such as oxidation/reduction, compartmentalization, exclusion, and immobilization [16] as the main natural defense mechanisms to arsenic. This review highlights our current understanding of the biochemistry and molecular biology involved in these natural arsenic metabolisms, and some successful examples of engineered microbes by harnessing these natural mechanisms for effective remediation.
在自然界中，原核生物和真核生物都进化出了广泛的途径，如氧化/还原、区隔化、排除和固定化[16]，作为砷的主要天然防御机制。本文综述了我们目前对这些天然砷代谢过程中涉及的生物化学和分子生物学的理解，以及利用这些天然机制进行有效修复的一些成功的工程微生物的例子。
