[唇唾液腺干燥综合征相关的黏膜相关淋巴组织型淋巴瘤：伴有淀粉样变性和 IgM 副蛋白血症的罕见组合]

[Sjögren-associated MALT-type lymphoma of labial salivary glands: rare constellation with amyloidosis and IgM-paraproteinemia].

作者信息

Flaig M J, Ihrler S

机构信息

Klinik und Poliklinik für Dermatologie und Allergologie, Klinikum Innenstadt, Ludwig-Maximilians-Universität München, Frauenlobstr 9-11, 80337 München.

出版信息

Pathologe. 2009 Nov;30(6):442-5. doi: 10.1007/s00292-009-1207-3.

DOI:10.1007/s00292-009-1207-3

PMID:19882292

Abstract

We report a complex and rare combination of clinical and histological findings in a 59-year-old female patient: severe sicca-syndrome due to M. Sjögren, marginal zone B-cell lymphoma (MALT-type) in labial salivary glands with localized amyloid deposition, IgM-paraproteinemia, and Bence-Jones proteinuria. The causal association of these findings could only be elucidated by intense interdisciplinary correlation of all findings.

摘要

我们报告了一名59岁女性患者临床和组织学检查结果复杂且罕见的组合情况：由干燥综合征引起的严重干燥综合征、唇唾液腺边缘区B细胞淋巴瘤（MALT型）伴局限性淀粉样沉积、IgM副蛋白血症和本-周蛋白尿。这些检查结果之间的因果关系只能通过对所有检查结果进行深入的多学科关联分析来阐明。