Department of Kinesiology, Center for Physical Activity and Health, Michigan State University, East Lansing, MI 48823, USA.
Obes Rev. 2010 Jul;11(7):492-507. doi: 10.1111/j.1467-789X.2009.00680.x. Epub 2009 Nov 5.
Research aimed at deciphering the aetiology of obesity and the metabolic syndrome remains focused on two behavioural factors, namely diet and physical activity, even though epidemiologic research suggests that these two cornerstones of treatment and prevention account for only a small-to-moderate portion of the variance in these phenotypes. In recent years, this observation has prompted the intensified investigation of the pathogenic potential of factors that extend beyond the traditional concept of energy imbalance and examine the putative causes of this imbalance. Psychosocial stress has emerged as one such factor, raising the need for researchers to be informed about this expansive and complex literature. The purpose of this review is twofold (i) To introduce obesity researchers to fundamental concepts and historically important theoretical developments in the stress field and (ii) To outline the dyadic and triadic interactions between stress, physical activity and the metabolic syndrome. Although the expansion of the research focus to multiple, diverse and interacting putative causal agents will certainly increase the complexity of the research enterprise, this step seems essential for the comprehension and effective response to the continuing rise in the prevalence of obesity and the metabolic syndrome.
研究旨在破译肥胖和代谢综合征的病因，仍然集中在两个行为因素上，即饮食和身体活动，尽管流行病学研究表明，这两个治疗和预防的基石只占这些表型中差异的小到中等部分。近年来，这一观察结果促使人们加强对超出传统能量失衡概念的致病因素的研究，并探讨这种失衡的潜在原因。心理社会压力就是这样一个因素，这就需要研究人员了解这一广泛而复杂的文献。本综述有两个目的：（i）向肥胖研究人员介绍压力领域的基本概念和历史上重要的理论发展；（ii）概述压力、身体活动和代谢综合征之间的二元和三元相互作用。尽管将研究重点扩展到多个、多样和相互作用的潜在因果因素肯定会增加研究工作的复杂性，但这一步骤对于理解和有效应对肥胖和代谢综合征的持续流行似乎是必要的。
