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In vivo uptake of 131I-5-iodo-2-deoxyuridine by malignant tumours in man.

作者信息

Philip P A, Bagshawe K D, Searle F, Green A J, Begent R H, Newlands E S, Rustin G J, Adam T

机构信息

Department of Medical Oncology, Charing Cross Hospital, London, UK.

出版信息

Br J Cancer. 1991 Jan;63(1):134-5. doi: 10.1038/bjc.1991.27.

DOI:10.1038/bjc.1991.27
PMID:1989652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1971655/
Abstract
摘要

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1
In vivo uptake of 131I-5-iodo-2-deoxyuridine by malignant tumours in man.人体内恶性肿瘤对131I - 5 -碘-2 -脱氧尿苷的体内摄取。
Br J Cancer. 1991 Jan;63(1):134-5. doi: 10.1038/bjc.1991.27.
2
The influence of high dose hydroxyurea on the incorporation of 5-iodo-2-deoxyuridine (IUdR) by human bone marrow and tumour cells in vivo.高剂量羟基脲对人骨髓和肿瘤细胞在体内摄取5-碘-2-脱氧尿苷（IUdR）的影响。
Br J Cancer. 1993 Apr;67(4):644-9. doi: 10.1038/bjc.1993.120.
3
Pilot clinical trial of 5-[125I]iodo-2'-deoxyuridine in the treatment of colorectal cancer metastatic to the liver.5-[¹²⁵I]碘-2'-脱氧尿苷治疗肝转移结直肠癌的临床试验
J Nucl Med. 1996 Apr;37(4 Suppl):25S-29S.
4
Does (124)Iodo-deoxyuridine measure cell proliferation in NSCLC? Initial investigations with PET imaging and radio-metabolite analysis.（124）碘脱氧尿苷能否用于测量非小细胞肺癌中的细胞增殖？PET成像和放射性代谢物分析的初步研究。
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5
The use of 5-(125I)iodo-2'-deoxyuridine for monitoring DNA synthesis in organ culture.5-（125I）碘-2'-脱氧尿苷用于监测器官培养中DNA合成的应用。
J Anat. 1976 Apr;121(Pt 2):323-9.
6
Selective uptake of toxic nucleoside (125IUdR) by resistant cancer.
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Radiotoxicity of 5-[125I]iodo-2'-deoxyuridine in mammalian cells following treatment with 5-fluoro-2'-deoxyuridine.5-氟-2'-脱氧尿苷处理后5-[¹²⁵I]碘-2'-脱氧尿苷对哺乳动物细胞的放射毒性
J Nucl Biol Med (1991). 1991 Jul-Sep;35(3):167-73.
8
[Incorporation of a 131-iodine-deoxycytidine monophosphate protamine complex into the DNA of tumor-bearing rats following partial synchronization with hydroxyurea].[用羟基脲进行部分同步化处理后，将131-碘脱氧胞苷一磷酸鱼精蛋白复合物掺入荷瘤大鼠的DNA中]
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[5-Iodo-2'-deoxyuridine in the assessment of the individual reaction of experimental tumors to irradiation].[5-碘-2'-脱氧尿苷在评估实验性肿瘤对辐射的个体反应中的应用]
Vopr Onkol. 1992;38(3):327-34.

引用本文的文献

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Characterizing tumors using metabolic imaging: PET imaging of cellular proliferation and steroid receptors.利用代谢成像对肿瘤进行特征描述：细胞增殖和类固醇受体的正电子发射断层显像（PET）成像
Neoplasia. 2000 Jan-Apr;2(1-2):71-88. doi: 10.1038/sj.neo.7900075.
2
Prediction of brain tumor therapy response by PET.通过正电子发射断层扫描（PET）预测脑肿瘤治疗反应
J Neurooncol. 1994;22(3):281-6. doi: 10.1007/BF01052934.

本文引用的文献

1
A REVIEW OF SOME ASPECTS OF 5-IODODEOXYURIDINE AND AZAURIDINE.
Cancer Res. 1963 Sep;23:1246-59.
2
Synthesis and biological activities of iododeoxyuridine, an analog of thymidine.胸腺嘧啶核苷类似物碘脱氧尿苷的合成及生物活性
Biochim Biophys Acta. 1959 Mar;32(1):295-6. doi: 10.1016/0006-3002(59)90597-9.
3
The genetic origin of drug resistance in neoplasms: implications for systemic therapy.肿瘤耐药性的遗传起源：对全身治疗的影响
Cancer Res. 1984 Sep;44(9):3643-53.
4
Drug resistance in cancer.癌症中的耐药性。
Cancer Treat Rep. 1984 Jan;68(1):87-99.
5
Alternative de novo and "salvage" pathways to thymidine triphosphate synthesis: possible implications for cancer chemotherapy.
Cancer Res. 1969 Dec;29(12):2398-403.
6
Changes in the deoxyribonucleoside triphosphate pools of mouse 5178Y lymphoma cells following exposure to methotrexate or 5-fluorouracil.暴露于甲氨蝶呤或5-氟尿嘧啶后小鼠5178Y淋巴瘤细胞中脱氧核糖核苷三磷酸库的变化。
Cancer Res. 1973 Dec;33(12):3086-90.
7
A cytotoxic DNA precursor is taken up selectively by human cancer xenografts.一种具有细胞毒性的DNA前体被人癌异种移植瘤选择性摄取。
Br J Cancer. 1987 Mar;55(3):299-302. doi: 10.1038/bjc.1987.58.
8
A phase I study of intravenous iododeoxyuridine as a clinical radiosensitizer.
Int J Radiat Oncol Biol Phys. 1985 Nov;11(11):1941-6. doi: 10.1016/0360-3016(85)90275-5.
9
Reversed-role chemotherapy for resistant cancer.针对耐药性癌症的角色逆转化疗。
Lancet. 1986 Oct 4;2(8510):778-81. doi: 10.1016/s0140-6736(86)90301-6.
10
Critical survey of experimental data on in vivo synchronization by hydroxyurea.关于羟基脲体内同步化实验数据的批判性综述。
Recent Results Cancer Res. 1975(52):187-205. doi: 10.1007/978-3-642-80940-8_22.