Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
J Am Chem Soc. 2009 Dec 2;131(47):17050-1. doi: 10.1021/ja906935c.
PhI(OAc)(2) is a common oxidant for Pd-catalyzed C-H bond functionalizations. Mechanistic hypotheses since the 1960s have suggested a Pd(II)/Pd(IV) mechanism. Here we present evidence for the relevance of bimetallic Pd(III) complexes to catalysis. A bimetallic Pd(III) acetate was isolated and can afford product by bimetallic reductive elimination.
PhI(OAc)(2) 是一种常用的钯催化 C-H 键功能化反应的氧化剂。自 20 世纪 60 年代以来，各种机理假说都提出了 Pd(II)/Pd(IV) 机理。在这里，我们提供了证据证明双金属 Pd(III)配合物与催化反应有关。分离得到了一个双金属 Pd(III)醋酸盐，它可以通过双金属还原消除来生成产物。
