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游离微血管皮瓣重建与硬腭填塞术治疗上颌骨切除术缺损的比较。

Microvascular free flap reconstruction versus palatal obturation for maxillectomy defects.

机构信息

Department of Plastic Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.

出版信息

Head Neck. 2010 Jul;32(7):860-8. doi: 10.1002/hed.21264.

Abstract

BACKGROUND

Palatal obturators and microvascular free flaps are both used to treat patients with maxillectomy defects, however, the optimal technique remains controversial.

METHODS

A retrospective analysis of 113 patients undergoing maxillectomy for cancer was performed. Seventy-three patients received an obturator and 40 patients were reconstructed with a free flap.

RESULTS

Speech intelligibility and postoperative diet were comparable between the obturator and free flap groups, except in cases of extensive (>50%) palatal defects, where free flap reconstruction was superior in both aspects (p = .019 and p = .043, respectively). The average time for presenting with a local recurrence in advanced cancer involving the palate was comparable in both groups (p = .33).

CONCLUSION

Moderate-sized maxillectomy defects involving the palate can be successfully treated with either an obturator or free flap reconstruction. Extensive defects have a better functional outcome with free flaps. Evidence does not suggest that free flap reconstructions delay diagnosis of local recurrences.

摘要

背景

腭护板和游离微血管皮瓣均可用于治疗上颌骨切除术患者的缺损,但最佳技术仍存在争议。

方法

对 113 例因癌症而行上颌骨切除术的患者进行回顾性分析。73 例患者接受了腭护板,40 例患者接受了游离皮瓣重建。

结果

腭护板组和游离皮瓣组在言语清晰度和术后饮食方面相当,除了广泛(>50%)腭部缺损的病例,游离皮瓣重建在这两方面均具有优势(p=0.019 和 p=0.043)。涉及腭部的晚期癌症的局部复发平均出现时间在两组间无差异(p=0.33)。

结论

中等大小的涉及腭部的上颌骨缺损可以通过腭护板或游离皮瓣重建成功治疗。游离皮瓣在广泛缺损方面具有更好的功能结果。没有证据表明游离皮瓣重建会延迟局部复发的诊断。

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