Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.
Subst Abus. 2009 Oct-Dec;30(4):306-17. doi: 10.1080/08897070903250241.
Stress is important in substance use disorders (SUDs). Mindfulness training (MT) has shown promise for stress-related maladies. No studies have compared MT to empirically validated treatments for SUDs. The goals of this study were to assess MT compared to cognitive behavioral therapy (CBT) in substance use and treatment acceptability, and specificity of MT compared to CBT in targeting stress reactivity. Thirty-six individuals with alcohol and/or cocaine use disorders were randomly assigned to receive group MT or CBT in an outpatient setting. Drug use was assessed weekly. After treatment, responses to personalized stress provocation were measured. Fourteen individuals completed treatment. There were no differences in treatment satisfaction or drug use between groups. The laboratory paradigm suggested reduced psychological and physiological indices of stress during provocation in MT compared to CBT. This pilot study provides evidence of the feasibility of MT in treating SUDs and suggests that MT may be efficacious in targeting stress.
压力在物质使用障碍（SUDs）中很重要。正念训练（MT）已显示出对与压力相关疾病的治疗潜力。目前还没有研究将 MT 与经过实证验证的 SUDs 治疗方法进行比较。本研究的目的是评估 MT 与认知行为疗法（CBT）相比在物质使用和治疗可接受性方面的差异，以及 MT 与 CBT 相比在针对应激反应方面的特异性。36 名患有酒精和/或可卡因使用障碍的个体被随机分配到门诊接受团体 MT 或 CBT 治疗。每周评估药物使用情况。治疗后，测量对个性化应激刺激的反应。有 14 人完成了治疗。两组在治疗满意度和药物使用方面没有差异。实验室范式表明，与 CBT 相比，MT 组在应激诱发期间的心理和生理压力指标降低。这项初步研究提供了 MT 治疗 SUDs 的可行性证据，并表明 MT 可能在针对压力方面有效。
