Institute of Organic Chemistry II and Advanced Materials, Ulm University, Albert-Einstein-Allee 11 89081 Ulm, Germany.
Org Lett. 2009 Nov 19;11(22):5098-101. doi: 10.1021/ol9022694.
Carbohydrate-functionalized oligothiophenes have been synthesized applying mild Sonogashira cross-coupling conditions. In an aqueous environment the amphiphilic hybrids self-assemble into chiral superstructures as a result of multiple hydrogen bond interactions and the helicity of the aggregates is controllable by the configuration of the carbohydrate unit. By means of atomic force microscopy highly ordered layer arrangements on substrates were characterized.
碳水化合物功能化的寡聚噻吩已通过温和的 Sonogashira 交叉偶联条件合成。在水相环境中，由于氢键的多重相互作用，两亲性杂化物自组装成手性超结构，并且通过糖单元的构型可控制聚集物的螺旋性。原子力显微镜用于表征衬底上高度有序的层排列。
