Institut Curie - CNRS, UMR144, Paris 75005, France.
Curr Biol. 2009 Sep 15;19(17):R823-7. doi: 10.1016/j.cub.2009.08.012.
The fission yeast Schizosaccharomyces pombe has served as an important model organism for investigating cellular morphogenesis. This unicellular rod-shaped fission yeast grows by tip extension and divides by medial fission. In particular, microtubules appear to define sites of polarized cell growth by delivering cell polarity factors to the cell tips. Microtubules also position the cell nucleus at the cell middle, marking sites of cell division. Here, we review the microtubule-dependent mechanisms that regulate cell shape and cell division in fission yeast.
裂殖酵母（Schizosaccharomyces pombe）作为一种重要的模式生物，用于研究细胞形态发生。这种单细胞的杆状裂殖酵母通过尖端延伸生长，并通过中部分裂进行分裂。特别是微管似乎通过将细胞极性因子递送到细胞尖端来定义极化细胞生长的位点。微管还将细胞核定位在细胞中部，标记细胞分裂的位点。在这里，我们综述了裂殖酵母中依赖微管的调节细胞形状和细胞分裂的机制。
