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隐花色素——一种潜在的磁受体:我们知道什么,我们想知道什么?

Cryptochromes--a potential magnetoreceptor: what do we know and what do we want to know?

机构信息

AG Neurosensorik (Animal Navigation), Institut für Biologie und Umweltwissenschaften, University of Oldenburg, 26111 Oldenburg, Germany.

出版信息

J R Soc Interface. 2010 Apr 6;7 Suppl 2(Suppl 2):S147-62. doi: 10.1098/rsif.2009.0411.focus. Epub 2009 Nov 11.

DOI:10.1098/rsif.2009.0411.focus
PMID:19906675
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2844001/
Abstract

Cryptochromes have been suggested to be the primary magnetoreceptor molecules underlying light-dependent magnetic compass detection in migratory birds. Here we review and evaluate (i) what is known about these candidate magnetoreceptor molecules, (ii) what characteristics cryptochrome molecules must fulfil to possibly underlie light-dependent, radical pair based magnetoreception, (iii) what evidence supports the involvement of cryptochromes in magnetoreception, and (iv) what needs to be addressed in future research. The review focuses primarily on our knowledge of cryptochromes in the context of magnetoreception.

摘要

隐花色素被认为是候鸟光依赖型磁罗盘检测的主要磁受体分子。在这里,我们回顾和评估(i)这些候选磁受体分子的已知特性,(ii)隐花色素分子必须具备哪些特征才能可能成为基于自由基对的光依赖磁受体,(iii)支持隐花色素参与磁受体的证据,以及(iv)未来研究中需要解决的问题。本综述主要侧重于我们在磁受体背景下对隐花色素的了解。

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本文引用的文献

1
Photoreceptor-based magnetoreception: optimal design of receptor molecules, cells, and neuronal processing.基于光感受器的磁受体感知:受体分子、细胞和神经元处理的最佳设计。
J R Soc Interface. 2010 Apr 6;7 Suppl 2(Suppl 2):S135-46. doi: 10.1098/rsif.2009.0456.focus. Epub 2010 Feb 3.
2
Visual but not trigeminal mediation of magnetic compass information in a migratory bird.候鸟中磁罗盘信息的视觉而非三叉神经介导
Nature. 2009 Oct 29;461(7268):1274-7. doi: 10.1038/nature08528.
3
The archaeal cofactor F0 is a light-harvesting antenna chromophore in eukaryotes.古细菌辅因子F0是真核生物中的一种光捕获天线发色团。
Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11540-5. doi: 10.1073/pnas.0812665106. Epub 2009 Jul 1.
4
Structural biology of DNA photolyases and cryptochromes.DNA光解酶和隐花色素的结构生物学
Curr Opin Struct Biol. 2009 Jun;19(3):277-85. doi: 10.1016/j.sbi.2009.05.003. Epub 2009 May 30.
5
Magnetic compass of birds is based on a molecule with optimal directional sensitivity.鸟类的磁罗盘基于一种具有最佳方向敏感性的分子。
Biophys J. 2009 Apr 22;96(8):3451-7. doi: 10.1016/j.bpj.2008.11.072.
6
Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes.(6-4)光裂合酶晶体结构中的功能基序为DNA修复光裂合酶和生物钟隐花色素提供了一个比较框架。
Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6962-7. doi: 10.1073/pnas.0809180106. Epub 2009 Apr 9.
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Effect of magnetic fields on cryptochrome-dependent responses in Arabidopsis thaliana.磁场对拟南芥隐花色素依赖性反应的影响。
J R Soc Interface. 2009 Dec 6;6(41):1193-205. doi: 10.1098/rsif.2008.0519. Epub 2009 Feb 25.
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Chemical magnetoreception in birds: the radical pair mechanism.鸟类的化学磁感应:自由基对机制。
Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):353-60. doi: 10.1073/pnas.0711968106. Epub 2009 Jan 7.
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Recognition and repair of UV lesions in loop structures of duplex DNA by DASH-type cryptochrome.DASH型隐花色素对双链DNA环结构中紫外线损伤的识别与修复。
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