European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Nucleic Acids Res. 2010 Jan;38(Database issue):D39-45. doi: 10.1093/nar/gkp998. Epub 2009 Nov 11.
The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena) is Europe's primary nucleotide sequence archival resource, safeguarding open nucleotide data access, engaging in worldwide collaborative data exchange and integrating with the scientific publication process. ENA has made significant contributions to the collaborative nucleotide archival arena as an active proponent of extending the traditional collaboration to cover capillary and next-generation sequencing information. We have continued to co-develop data and metadata representation formats with our collaborators for both data exchange and public data dissemination. In addition to the DDBJ/EMBL/GenBank feature table format, we share metadata formats for capillary and next-generation sequencing traces and are using and contributing to the NCBI SRA Toolkit for the long-term storage of the next-generation sequence traces. During the course of 2009, ENA has significantly improved sequence submission, search and access functionalities provided at EMBL-EBI. In this article, we briefly describe the content and scope of our archive and introduce major improvements to our services.
欧洲核苷酸档案库（ENA；http://www.ebi.ac.uk/ena）是欧洲主要的核苷酸序列档案资源，保障开放的核苷酸数据访问，从事全球合作的数据交换，并与科学出版过程相结合。ENA 作为将传统合作扩展到涵盖毛细管和下一代测序信息的积极支持者，为协作核苷酸档案领域做出了重大贡献。我们继续与合作者共同开发数据和元数据表示格式，用于数据交换和公共数据发布。除了 DDBJ/EMBL/GenBank 特征表格式外，我们还共享毛细管和下一代测序轨迹的元数据格式，并正在使用和为长期存储下一代序列轨迹贡献 NCBI SRA 工具包。在 2009 年期间，ENA 极大地改进了在 EMBL-EBI 提供的序列提交、搜索和访问功能。在本文中，我们简要描述了我们的档案库的内容和范围，并介绍了对我们服务的主要改进。
