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C3H细胞暴露于脉冲超声后细胞转化频率未增加。

Lack of increase in cell transformation frequency of C3H cells after exposure to pulsed ultrasound.

作者信息

Zhu W H, Miller M W, Cox C

机构信息

Department of Biophysics, University of Rochester, NY 14642.

出版信息

Ultrasonics. 1991 Jan;29(1):81-4. doi: 10.1016/0041-624x(91)90178-b.

DOI:10.1016/0041-624x(91)90178-b
PMID:1990723
Abstract

Liebeskind et al. reported that ultrasound from a diagnostic ultrasound unit caused an increase in cell transformation of in vitro C3H cells. The objective of this study was to attempt verification of this result, using the same cell line and a similar ultrasound exposure regimen. Four experiments were undertaken, each involving an ultrasound, X-ray (positive control) and sham exposure regimen. There was no increase in cell transformation frequency with the ultrasound exposure, but a small and statistically significant increase with the X-ray regimen.

摘要

利伯斯金德等人报告称,诊断超声设备发出的超声波会导致体外培养的C3H细胞的细胞转化增加。本研究的目的是尝试使用相同的细胞系和类似的超声暴露方案来验证这一结果。进行了四项实验,每项实验都包括超声、X射线(阳性对照)和假暴露方案。超声暴露并未使细胞转化频率增加,但X射线方案导致了小幅且具有统计学意义的增加。

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