Division of Newborn Medicine, Department of Pediatrics, Floating Hospital for Children at Tufts Medical Center, Boston, MA, USA.
J Perinatol. 2010 Jul;30(7):441-6. doi: 10.1038/jp.2009.182. Epub 2009 Nov 12.
Obesity has reached epidemic proportions in our patients who are of childbearing age, with pregnant patients of normal weight being in the minority. The pregnancy-related complications attributable to obesity affect not only the pregnant women, but also her fetus and potentially both mother and child for their lifetimes. Pregnancy is associated with altered immunity. The physiologic state of chronic inflammation in obesity affects systemic immunity and metabolism, and may be associated with several of the complications associated with maternal obesity. The interplay between pregnancy, obesity and inflammation may have far-reaching implications for fertility, pregnancy, the fetus and neonate.
肥胖在我们的育龄患者中已达到流行程度，正常体重的孕妇占少数。肥胖引起的与妊娠相关的并发症不仅影响孕妇，还影响她的胎儿，并可能对母亲和孩子的一生都有潜在影响。妊娠伴随着免疫改变。肥胖的慢性炎症生理状态会影响全身免疫和代谢，并可能与与母体肥胖相关的几种并发症有关。妊娠、肥胖和炎症之间的相互作用可能对生育能力、妊娠、胎儿和新生儿产生深远影响。
