合成一种光笼氨基氧基烷硫醇。
Synthesis of a photo-caged aminooxy alkane thiol.
机构信息
Department of Chemistry and Biochemistry, University of California, Los Angeles, 607 Charles E. Young Drive South, Los Angeles, CA 90095-1596, USA.
出版信息
Org Biomol Chem. 2009 Dec 7;7(23):4954-9. doi: 10.1039/b904195h. Epub 2009 Oct 6.
Abstract
A photo-caged aminooxy alkane thiol synthesized in 7 steps and 15% overall yield was used to form a self-assembled monolayer (SAM). Photo-deprotection on the surface was confirmed by FT-IR spectroscopy and contact angle goniometry. Conjugation of a small molecule ketone, ethyl levulinate, further confirmed the presence of aminooxy groups on the surface.
摘要
合成了一种 7 步总产率为 15%的光笼氨基氧基烷硫醇，用于形成自组装单层（SAM）。通过傅里叶变换红外光谱（FT-IR）和接触角测量法证实了表面的光解保护。小分子酮（乙基戊内酯）的偶联进一步证实了表面存在氨基氧基。
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