Research Centre of Bioorganic Chemistry, Department of Chemistry, Chulalongkorn University, Bangkok, 10330, Thailand.
J Nat Prod. 2009 Dec;72(12):2188-91. doi: 10.1021/np900640u.
Three new protolimonoids, protoxylocarpins F-H (1-3), along with 11 known limonoids, were isolated from seed kernels of Xylocarpus granatum. Their structures were elucidated on the basis of extensive spectroscopic data analyses. All compounds isolated were evaluated for cytotoxic activity against five human tumor cell lines.
从厚壳桂的种仁中分离得到了三种新的原小檗堿类化合物protoxylocarpins F-H（1-3），以及 11 种已知的柠檬苦素类化合物。基于广泛的光谱数据分析，阐明了它们的结构。所有分离得到的化合物均对五种人肿瘤细胞系进行了细胞毒性活性评价。
