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灰毛浆果楝叶中的三萜类柠檬苦素。

Trijugin-type limonoids from the leaves of Cipadessa cinerascens.

作者信息

Di Ying-Tong, He Hong-Ping, Liu Hai-Yang, Yi Ping, Zhang Zhen, Ren Yan-Li, Wang Jun-Song, Sun Qian-Yun, Yang Fu-Mei, Fang Xin, Li Shun-Lin, Zhu Hua-Jie, Hao Xiao-Jiang

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.

出版信息

J Nat Prod. 2007 Aug;70(8):1352-5. doi: 10.1021/np0700624. Epub 2007 Jul 26.

Abstract

Four new trijugin-type limonoids, cipatrijugins A-D (1-4), together with the known cipadesin A (5), were isolated from the leaves of Cipadessa cinerascens, and their structures were elucidated on the basis of spectroscopic and computational methods. The ability of compounds 1-5 to inhibit the growth of the A549 and K562 tumor cell lines was evaluated.

摘要

从灰毛浆果楝(Cipadessa cinerascens)的叶子中分离出了四种新的三降香豆素型柠檬苦素,即西帕降香豆素A-D(1-4),以及已知的西帕德辛A(5),并通过光谱和计算方法阐明了它们的结构。评估了化合物1-5抑制A549和K562肿瘤细胞系生长的能力。

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