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通过 E1cB 消除 N-N'键而不是还原反应，从二乙氧羰基肼衍生物合成氨基甲酸酯。

Synthesis of carbamates from diethoxycarbonyl hydrazine derivatives by E1cB eliminative cleavage of the N-N'-bond rather than reduction.

机构信息

Department of Chemistry and Biochemistry, University of Texas at Austin, 1 University Station A5300, Austin, Texas 78712-1167, USA.

出版信息

Org Lett. 2009 Dec 17;11(24):5646-8. doi: 10.1021/ol902313v.

DOI:10.1021/ol902313v
PMID:19908859
Abstract

Treatment of diethoxycarbonyl hydrazine derivatives with methyl bromoacetate/Cs(2)CO(3)/MeCN at 50 degrees C followed by heating to 80 degrees C resulted in N-N' bond cleavage to the corresponding carbamates.

摘要

在 50°C 下，用溴乙酸甲酯/Cs(2)CO(3)/MeCN 处理二乙氧基羰基肼衍生物，然后加热至 80°C，导致 N-N' 键断裂，生成相应的氨基甲酸酯。

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