Departments of Neurology and Public Health (Epidemiology), College of Physicians and Surgeons of Columbia University, Gertrude H. Sergievsky Center, 630 West 168th Street, New York, NY 10032, U.S.A.
Epilepsia. 1997 Nov;38(11 Suppl):S26-9. doi: 10.1111/j.1528-1157.1997.tb06120.x.
Understanding of mechanisms and the development of interventions to prevent sudden unexpected death in epilepsy (SUDEP) can be enhanced only through multicenter studies. Although current definitions are useful and congruent, there is insufficient guidance to allow others to duplicate studies. A working algorithm should be developed, preferably through review of current series, along with alternative definitions to allow external comparison with cardiovascular studies.
只有通过多中心研究才能更好地了解预防癫痫猝死 (SUDEP) 的机制和干预措施的发展。尽管目前的定义是有用且一致的,但缺乏足够的指导,无法让其他人重复研究。应制定一个工作算法,最好通过审查当前的系列研究,并提出替代定义,以便与心血管研究进行外部比较。