Epilepsy Research Group/Neuroepidemiology, Institute of Neurology, 33 Queen Square, London, England.
Epilepsia. 1997 Nov;38(11 Suppl):S15-9. doi: 10.1111/j.1528-1157.1997.tb06117.x.
Recent studies indicate that the overall mortality rate for persons with epilepsy is elevated two- or threefold compared with the general population. The standardized mortality ratio (SMR) is greatest in the first few years after diagnosis and in symptomatic epilepsies. Idiopathic epilepsies also have a small increase in SMR. The sudden unexpected death rate in those with epilepsy (SUDEP) depends on the population examined. In the general population of persons with epilepsy, the risk is between 1:500 and 1:1,000 person-years. For those with severe epilepsy or other neurologic impairments, the risk appears to be 1:200 person-years. The risk in children remains uncertain. Estimates of mortality should be borne in mind when patients are counseled about the risks and benefits of various treatment strategies.
最近的研究表明，与普通人群相比，癫痫患者的总死亡率高出两到三倍。标准化死亡率（SMR）在诊断后的头几年和症状性癫痫中最高。特发性癫痫的 SMR 也略有增加。癫痫患者的突发性意外死亡率（SUDEP）取决于所检查的人群。在一般癫痫患者人群中，风险为每 500 至 1000 人年 1 例。对于那些患有严重癫痫或其他神经功能障碍的患者，风险似乎为每 200 人年 1 例。儿童的风险仍然不确定。在为患者提供有关各种治疗策略的风险和益处的咨询时，应考虑到死亡率的估计。
