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脊髓损伤患者神经病理性疼痛发生和慢性化的风险因素有哪些?

What are the risk factors of occurence and chronicity of neuropathic pain in spinal cord injury patients?

机构信息

Fondation Rothschild, 25, rue Manin, 75019 Paris, France.

出版信息

Ann Phys Rehabil Med. 2009 Mar;52(2):111-23. doi: 10.1016/j.rehab.2008.12.003. Epub 2009 Jan 22.

Abstract

OBJECTIVE

Analyze the epidemiological data on neuropathic pain in spinal cord injury patients and determine the risk factors for its occurrence and chronicity.

METHOD

Review and analysis of the literature.

RESULTS

Epidemiological data report that 40% of spinal cord injury (SCI) patients suffer from neuropathic pain and 40% of these patients report an intense neuropathic pain. Some factors do not seem to be predictive for the onset of neuropathic pain: the level of injury, complete or incomplete injury, the existence of an initial surgery, sex. However, old age at the time of injury, bullet injury as the cause of trauma, early onset of pain in the weeks following the injury, their initial nature, intensity and continuous pain, as well as associated symptoms all appear to be negative prognostic factors.

CONCLUSION

Neuropathic pain in SCI patients is a major issue, its determining factors still need to be evaluated properly by refining the epidemiological data.

摘要

目的

分析脊髓损伤患者神经性疼痛的流行病学数据,确定其发生和慢性化的危险因素。

方法

文献回顾与分析。

结果

流行病学数据报告称,40%的脊髓损伤(SCI)患者患有神经性疼痛,其中 40%的患者报告存在强烈的神经性疼痛。一些因素似乎不能预测神经性疼痛的发生:损伤水平、完全或不完全损伤、是否存在初始手术、性别。然而,受伤时的年龄较大、枪弹伤作为创伤的原因、受伤后数周内疼痛的早期发作、其初始性质、强度和持续疼痛以及伴随症状似乎都是预后不良的因素。

结论

脊髓损伤患者的神经性疼痛是一个主要问题,其决定因素仍需通过完善流行病学数据来进行适当评估。

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