Roca Bernardino
Hospital General de Castellón, Universidad de Valencia, Castellón de la Plana, España.
Acta Otorrinolaringol Esp. 2009 Nov-Dec;60(6):456-8. doi: 10.1016/j.otorri.2008.11.001. Epub 2009 Sep 25.
We report the case of a 77-year-old man who presented nasal obstruction sensation and epistaxis. Otorhinolaryngological examination revealed occupation of the left nasal passage and the left maxillary sinus by an inflammatory tumour, the biopsy results of which were inconclusive. While diagnostic tests where being carried out, the patient presented a severe systemic condition consisting mainly of anaemia, acute renal failure, and cavitated diffuse bilateral lung infiltrates. In the light of the results of anti-neutrophilic cytoplasmic antibodies and renal biopsy, Wegener's granulomatosis was diagnosed and treatment for the disease was instituted with a favourable response. Finally, clinical manifestations of Wegener's granulomatosis are reviewed, with especial emphasis on otolaryngologic complaints.
我们报告了一例77岁男性患者，其出现鼻塞感和鼻出血症状。耳鼻喉科检查发现左侧鼻腔和左侧上颌窦被炎性肿瘤占据，活检结果不明确。在进行诊断性检查时，患者出现严重的全身状况，主要包括贫血、急性肾衰竭以及双侧肺部弥漫性空洞浸润。根据抗中性粒细胞胞浆抗体和肾活检结果，诊断为韦格纳肉芽肿，并对该疾病进行治疗，治疗反应良好。最后，对韦格纳肉芽肿的临床表现进行了综述，特别强调了耳鼻喉科的症状。
