EMBL - European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom.
C R Biol. 2009 Nov;332(11):1050-8. doi: 10.1016/j.crvi.2009.09.003.
Integration of biological data of various types and the development of adapted bioinformatics tools represent critical objectives to enable research at the systems level. The European Network of Excellence ENFIN is engaged in developing an adapted infrastructure to connect databases, and platforms to enable both the generation of new bioinformatics tools and the experimental validation of computational predictions. With the aim of bridging the gap existing between standard wet laboratories and bioinformatics, the ENFIN Network runs integrative research projects to bring the latest computational techniques to bear directly on questions dedicated to systems biology in the wet laboratory environment. The Network maintains internally close collaboration between experimental and computational research, enabling a permanent cycling of experimental validation and improvement of computational prediction methods. The computational work includes the development of a database infrastructure (EnCORE), bioinformatics analysis methods and a novel platform for protein function analysis FuncNet.
整合各种类型的生物数据和开发适应的生物信息学工具是实现系统水平研究的关键目标。欧洲卓越网络 ENFIN 致力于开发一种适应的基础设施，连接数据库和平台，以生成新的生物信息学工具并对计算预测进行实验验证。为了弥合标准湿实验室和生物信息学之间存在的差距，ENFIN 网络开展了综合性研究项目，将最新的计算技术直接应用于湿实验室环境中专门用于系统生物学的问题。该网络在实验和计算研究之间保持着紧密的内部合作，使实验验证和计算预测方法的改进能够持续循环。计算工作包括开发数据库基础设施（EnCORE）、生物信息学分析方法和用于蛋白质功能分析的新平台 FuncNet。
