Department of Radiology, University of New Mexico School of Medicine, MSC10 5530, Albuquerque, NM, 87131-0001, USA.
Skeletal Radiol. 2010 Jul;39(7):669-73. doi: 10.1007/s00256-009-0825-4. Epub 2009 Nov 13.
To determine if new onset of low back pain in adults could be secondary to lumbar spondylolysis by establishing the age-related prevalence in the general population by examining patients undergoing computed tomography (CT) for reasons unrelated to back pain.
The records of 2,555 patients who had undergone abdominal and pelvic CT in 2008 were reviewed electronically. In order to determine a true representation of the general population, we reviewed all indications for CT, excluding patients with a primary complaint of low back pain as the primary indication for imaging. Equal numbers of patients were separated into age groups by decade to ensure an even distribution of ages for statistical analysis. Patients older than 70 years were grouped together to provide case numbers comparable to those of the other decades. Logistic regression analysis was performed to evaluate the significance of the results. Three board-certified radiologists, including two musculoskeletal fellows and a radiology resident, retrospectively evaluated CT scans for lumbar spondylolysis, including unilateral and bilateral defects.
Of the 2,555 cases evaluated, there were 203 positive cases of defects of the lumbar pars interarticularis. This corresponded to an overall prevalence of 8.0%. Prevalence per decade was fairly evenly distributed and ranged from 7.0%( ages 30-39 years) to 9.2% (ages 70 years and above). Prevalence of ages 20-49 years was 7.9%, and that of ages 50 years and older was 8.0%. Male to female ratio was 1.5:1. Logistic regression showed no significant increase in spondylolysis based on age.
No significant increase in the prevalence of lumbar spondylolysis was demonstrated in patients older than 20 years. This suggests that the development of symptomatic lumbar pars defects do not occur in this population and should not be considered as a rare but potentially treatable cause of new onset low back pain in adults. This study demonstrated an overall prevalence of pars defects of 8.0% in our population. As demonstrated in previous studies, the male to female ratio of 1.5:1 was a statistically significant difference.
通过检查因与腰痛无关的原因接受计算机断层扫描(CT)的患者,确定成年人新发腰痛是否是腰椎峡部裂引起的,从而确定该人群中腰椎峡部裂的年龄相关性患病率。
对 2008 年接受腹部和骨盆 CT 检查的 2555 例患者的病历进行了电子回顾。为了确定对一般人群的真实代表性,我们回顾了所有 CT 检查的指征,排除了以腰痛为主要影像学指征的患者。将患者按年龄组每十年分为一组,以确保统计分析中年龄分布均匀。70 岁以上的患者被分为一组,以便与其他年龄组的病例数量相媲美。采用逻辑回归分析评估结果的显著性。三位经过董事会认证的放射科医生,包括两名肌肉骨骼研究员和一名放射科住院医师,回顾性地评估了 CT 扫描是否存在腰椎峡部裂,包括单侧和双侧缺陷。
在评估的 2555 例病例中,有 203 例存在腰椎小关节突间关节骨裂,这相当于总体患病率为 8.0%。每十年的患病率分布均匀,范围为 7.0%(30-39 岁)至 9.2%(70 岁及以上)。20-49 岁年龄组的患病率为 7.9%,50 岁及以上年龄组的患病率为 8.0%。男女比例为 1.5:1。逻辑回归显示,年龄与峡部裂之间无显著相关性。
在 20 岁以上的患者中,腰椎峡部裂的患病率没有显著增加。这表明,有症状的腰椎小关节突缺损不会发生在这一人群中,不应将其视为成人新发腰痛的罕见但潜在可治疗的原因。本研究显示,我们人群中小关节突缺损的总体患病率为 8.0%。与之前的研究一样,男女比例为 1.5:1 是一个具有统计学意义的差异。