Department of Pathology, Hippokration General Hospital of Thessaloniki, Thessaloniki, Greece.
Pediatr Pulmonol. 2009 Dec;44(12):1240-3. doi: 10.1002/ppul.21142.
Mediastinal gastroenteric cyst is an uncommon congenital malformation and a distinct histopathological entity within the family of foregut duplication cysts. This lesion is mainly encountered in neonates and infants. Histologically, it is characterized by double-layered smooth muscle wall and gastric lining mucosa. We report on a case of a 2-day-old girl, with a posterior mediastinal cystic mass associated with T3-T4 hemivertebrae, presenting with severe respiratory distress. The cyst was multilocular, surgically removed, and histopathologic analysis revealed that it was of gastroenteric type. However, in numerous areas of the lesion, respiratory-type epithelium was observed, as well as pancreatic tissue. After removal of the lesion the patient made an uneventful recovery and shows no signs of long-term pulmonary sequelae. We failed to demonstrate in the available literature the presence of this variable epithelial lining within a single mediastinal foregut cyst. In addition, pancreatic tissue within an intrathoracic enteric cyst has been reported only twice.
纵隔肠源性囊肿是一种罕见的先天性畸形，是前肠重复囊肿家族中的一种独特的组织病理学实体。这种病变主要发生在新生儿和婴儿中。组织学上，它的特征是双层平滑肌壁和胃黏膜衬里。我们报告了一例 2 天大的女婴，其在后纵隔有一个囊性肿块，伴有 T3-T4 半椎体，表现为严重的呼吸窘迫。囊肿呈多房性，手术切除，组织病理学分析显示为肠型。然而，在病变的许多区域观察到呼吸型上皮以及胰腺组织。切除病变后，患者恢复顺利，没有出现长期肺部后遗症的迹象。我们在现有的文献中未能发现单个纵隔前肠囊肿内存在这种可变的上皮衬里。此外，胸腔内肠源性囊肿内的胰腺组织仅报告过两次。
