Szewczyk A, Claeys D, Mertens W, Azzi A
Institut für Biochemie und Molekularbiologie, Universität Bern, Switzerland.
Biochim Biophys Acta. 1991 Jan 23;1073(1):209-12. doi: 10.1016/0304-4165(91)90204-t.
A new photoaffinity probe, 5-(1-hydroxy-4-azidophenylazo)-1,2,3-benzenetricarboxylic acid, was synthesized and characterized. This reagent can be potentially used in photoaffinity labeling of the mitochondrial tricarboxylate carrier, as well as of enzymes interacting with tricarboxylic acids. Inhibition and labeling of the mitochondrial tricarboxylate carrier is presented.
合成并表征了一种新的光亲和探针5-(1-羟基-4-叠氮基苯偶氮)-1,2,3-苯三甲酸。该试剂可潜在地用于线粒体三羧酸载体以及与三羧酸相互作用的酶的光亲和标记。文中展示了对线粒体三羧酸载体的抑制和标记。
