[脊髓灰质炎患者体内抗脊髓灰质炎病毒沉淀抗体]
[Precipitation antibodies against poliovirus in patients with poliomyelitis].
作者信息
Ruiz-Gómez J, Bustamante M E
出版信息
Arch Invest Med (Mex). 1977;8(2):103-12.
Sera from 26 children bearing poliomyelitis caused by virus tipe I and from 47 cases with paralysis of different etiology (non-poliomyelitic) were tested against antigen of poliovirus types I, II and III with an agar-immunoprecipitation reaction. All sera with neutralizing antibodies with titres of 1:1250 gave positive results in immunodifusion tests. The percentage of positiveness decrease with lower titres. No false positive reactions were found. Immunodiffusion test with antigens of poliovirus were positive in 100% of sera from patients with poliomyelitis and only in 30% in sera from patients with non polio paralysis.
对26例由I型病毒引起的小儿麻痹症患儿的血清以及47例不同病因（非小儿麻痹症）导致瘫痪的病例血清，采用琼脂免疫沉淀反应，检测I、II、III型脊髓灰质炎病毒抗原。所有中和抗体效价为1:1250的血清在免疫扩散试验中均呈阳性结果。效价越低，阳性百分比越低。未发现假阳性反应。脊髓灰质炎病毒抗原免疫扩散试验在小儿麻痹症患者血清中的阳性率为100%，在非小儿麻痹症瘫痪患者血清中仅为30%。
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