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失眠的发生率和时间模式:一项初步研究。

The incidence and temporal patterning of insomnia: a pilot study.

机构信息

Behavioral Sleep Medicine Program, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.

出版信息

J Sleep Res. 2010 Mar;19(1 Pt 1):31-5. doi: 10.1111/j.1365-2869.2009.00768.x. Epub 2009 Nov 11.

DOI:10.1111/j.1365-2869.2009.00768.x
PMID:19912510
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5321210/
Abstract

To date very little research has been conducted on night-to-night variability in the incidence of insomnia. It is unclear from prior research whether subjects with primary insomnia (PI) exhibit good sleep (or better than average sleep) on some interval basis. In the present study, pilot data are provided on: (1) the frequency with which 'good sleep' occurs in subjects with PI; and (2) whether these events occur in a non-random manner. Ten subjects with PI participated in this 'naturalistic' study. All subjects completed daily sleep diaries for a minimum of 20 days. None of the subjects received treatment for their insomnia during the monitoring period. The night-to-night data were evaluated by typing each night's sleep as 'Good' or 'Bad', and then by determining the number of bad nights that occurred prior to a good night for each subject. Good and bad nights were typed in two ways: (1) using a > or =85% cut-off and (2) using a better than the individual's mean sleep efficiency (idiographic cut-off). Subjects exhibited good sleep on between 29% (>85% criteria) and 55% (idiographic criteria) of the nights evaluated. The temporal patterning analysis (based on an idiographic cut-off) revealed that better than average sleep most frequently occurred (>89% of instances) following one to three nights of poor sleep. These data suggest that insomnia severity may be mediated/moderated by sleep homeostasis and that the homeostat, or input to the homeostat, may be abnormal in patients with PI.

摘要

迄今为止,关于失眠发生率的夜间变化,研究非常有限。先前的研究尚不清楚原发性失眠(PI)患者是否在某些间隔基础上表现出良好的睡眠(或优于平均睡眠)。在本研究中,提供了关于以下方面的初步数据:(1)PI 患者“良好睡眠”发生的频率;以及(2)这些事件是否以非随机方式发生。10 名 PI 患者参与了这项“自然主义”研究。所有患者至少完成了 20 天的日常睡眠日记。在监测期间,没有患者接受失眠治疗。通过将每晚的睡眠标记为“良好”或“不良”,然后确定每个患者在良好夜晚之前不良夜晚的数量来评估夜间到夜间的数据。通过两种方式标记良好和不良的夜晚:(1)使用>或=85%的截止值,(2)使用优于个体平均睡眠效率(个体化截止值)。在评估的夜间中,患者表现出良好睡眠的比例在 29%(>85%标准)到 55%(个体化标准)之间。时间模式分析(基于个体化截止值)表明,良好的睡眠最常发生在(>89%的情况下)经历一到三晚的不良睡眠之后。这些数据表明,失眠严重程度可能受到睡眠稳态的调节/缓和,并且 PI 患者的稳态或稳态输入可能异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/938d/5321210/3d8805ce9ea5/nihms294440f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/938d/5321210/017f05298bf5/nihms294440f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/938d/5321210/3d8805ce9ea5/nihms294440f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/938d/5321210/017f05298bf5/nihms294440f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/938d/5321210/3d8805ce9ea5/nihms294440f2.jpg

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