Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
J Am Soc Echocardiogr. 2010 Jan;23(1):1-8. doi: 10.1016/j.echo.2009.10.005. Epub 2009 Nov 13.
The aim of this study was to validate a novel method of determining vena contracta area (VCA) and quantifying mitral regurgitation using multibeam high-pulse repetition frequency (HPRF) color Doppler.
The Doppler signal was isolated from the regurgitant jet, and VCA was found by summing the Doppler power from multiple beams within the vena contracta region, where calibration was done with a reference beam. In 27 patients, regurgitant volume was calculated as the product of VCA and the velocity-time integral of the regurgitant jet, measured by continuous-wave Doppler, and compared with regurgitant volume measured by magnetic resonance imaging (MRI).
Spearman's rank correlation and the 95% limits of agreement between regurgitant volume measured by MRI and by multibeam HPRF color Doppler were r(s) = 0.82 and -3.0 +/- 26.2 mL, respectively.
For moderate to severe mitral regurgitation, there was good agreement between MRI and multibeam HPRF color Doppler. Agreement was lower in mild regurgitation.
本研究旨在验证一种使用多波束高频重复频率(HPRF)彩色多普勒确定射流收缩区(VCA)和量化二尖瓣反流的新方法。
从反流射流中分离出多普勒信号,并通过在射流收缩区的多个波束中求和多普勒功率来找到 VCA,其中通过参考波束进行校准。在 27 名患者中,反流量通过 VCA 与连续波多普勒测量的反流射流速度时间积分的乘积计算,并与磁共振成像(MRI)测量的反流量进行比较。
MRI 和多波束 HPRF 彩色多普勒测量的反流量之间的 Spearman 秩相关系数和 95%一致性界限分别为 r(s) = 0.82 和 -3.0 +/- 26.2 mL。
对于中度至重度二尖瓣反流,MRI 和多波束 HPRF 彩色多普勒之间具有良好的一致性。在轻度反流中,一致性较低。