冷冻解冻精子的体外受精技术：一种保留霍奇金病患者生殖潜能的方法。
In vitro fertilization techniques with frozen-thawed sperm: a method for preserving the progenitive potential of Hodgkin patients.
作者信息
Tournaye H, Camus M, Bollen N, Wisanto A, Van Steirteghem A C, Devroey P
机构信息
Centre for Reproductive Medicine, Vrije Universiteit Brussel, Belgium.
出版信息
Fertil Steril. 1991 Feb;55(2):443-5. doi: 10.1016/s0015-0282(16)54147-8.
The banked sperm of 5 of 13 Hodgkin patients was thawed for assisted reproduction. The post-thaw sperm characteristics were extremely impaired. Nevertheless, in 80% of all trials fertilization in vitro was obtained and conceptus could be transferred. All spouses became pregnant and seven healthy infants were born. One could recommend every Hodgkin patient to bank his sperm before chemotherapy. In vitro fertilization techniques with this frozen-thawed sperm reveal promising results in comparison with artificial insemination to maintain the reproductive capacity of male Hodgkin patients.
13例霍奇金病患者中有5例的冷冻精子被解冻用于辅助生殖。解冻后的精子特征严重受损。然而，在所有试验中，80%获得了体外受精，并且可以移植胚胎。所有配偶均成功怀孕，7名健康婴儿出生。可以建议每位霍奇金病患者在化疗前冷冻精子。与人工授精相比，使用这种冻融精子的体外受精技术在维持男性霍奇金病患者生殖能力方面显示出有希望的结果。
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