Baldauf Jörg, Oertel J, Gaab Michael R, Schroeder Henry W S
Department of Neurosurgery, Ernst-Moritz-Arndt University, Sauerbruchstrasse, 17475, Greifswald, Germany.
Childs Nerv Syst. 2007 Jun;23(6):623-6. doi: 10.1007/s00381-007-0335-4. Epub 2007 Apr 6.
Endoscopic third ventriculostomy (ETV) for the treatment of hydrocephalus of different etiologies is still controversial in children younger than 2 years of age. The success rate of ETV in this group of patients is analyzed in this study.
The series consisted of 21 patients treated with ETV. The mean age of the patients was 6.7 months, ranging from 9 days to 15 months (16 patients were younger than 1 year). The study included hydrocephalus due to idiopathic aqueductal stenosis (eight) and other congenital anomalies (four) as well as posthemorrhagic (three) and tumor-related occlusive hydrocephalus (three). Two patients presented with shunt infection and one with a shunt failure. ETV was considered to be successful when shunting could be avoided.
ETV was successful in nine patients, with a mean follow-up period of 26.2 months. The procedure was successful in four patients with idiopathic aqueductal stenosis, in two with other congenital anomalies, in one posthemorrhagic, and in two with a tumor-related hydrocephalus. In 12 patients, the ETV was unsuccessful after a mean follow-up of 3.3 months. These patients required a shunt. Ten of them were less than 1 year old when ETV was performed. In one tumor-related hydrocephalus, a shunt was inserted after a meningitis after tumor removal.
The success of ETV in children younger than 2 years of age suffering from non-communicating hydrocephalus seems to be dependent on both age and etiology. Our results show an overall success rate of 43%. In 37.5% of the children younger than 1 year of age, ETV was successful. ETV in patients with hydrocephalus due to idiopathic aqueductal stenosis seems to be more beneficial than in other causes of hydrocephalus.
对于2岁以下儿童因不同病因引起的脑积水,内镜下第三脑室造瘘术(ETV)仍存在争议。本研究分析了该组患者ETV的成功率。
该系列包括21例行ETV治疗的患者。患者的平均年龄为6.7个月,范围从9天至15个月(16例患者年龄小于1岁)。该研究包括特发性导水管狭窄导致的脑积水(8例)、其他先天性异常(4例)以及出血后(3例)和肿瘤相关的梗阻性脑积水(3例)。2例患者出现分流感染,1例出现分流失败。当可以避免分流时,ETV被认为是成功的。
9例患者ETV成功,平均随访期为26.2个月。该手术在4例特发性导水管狭窄患者、2例其他先天性异常患者、1例出血后患者和2例肿瘤相关脑积水患者中成功。12例患者在平均随访3.3个月后ETV失败。这些患者需要进行分流。其中10例在进行ETV时年龄小于1岁。在1例肿瘤相关脑积水患者中,肿瘤切除后发生脑膜炎,随后插入了分流管。
2岁以下非交通性脑积水儿童ETV的成功似乎取决于年龄和病因。我们的结果显示总体成功率为43%。在1岁以下的儿童中,37.5%的ETV成功。特发性导水管狭窄导致脑积水的患者进行ETV似乎比其他脑积水病因更有益。