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星状神经节阻滞对兔组织血流再分布的影响。

Redistribution of tissue blood flow after stellate ganglion block in the rabbit.

机构信息

Department of Dental Anesthesiology, Tokyo Dental College, Chiba, Japan.

出版信息

Reg Anesth Pain Med. 2009 Nov-Dec;34(6):553-6. doi: 10.1097/aap.0b013e3181b4c505.

DOI:10.1097/aap.0b013e3181b4c505
PMID:19916209
Abstract

BACKGROUND AND OBJECTIVES

The goal of this study was to compare tissue blood flow at various sites before and after stellate ganglion block (SGB) and to discuss the redistribution of tissue blood flow after SGB.

METHODS

We studied 16 male Japanese white rabbits. For SGB, the tip of a 26-gauge needle was placed on the left transverse process of the cervical vertebra, 1 to 2 mm caudal to the cricoid cartilage. Either 0.2 mL of 1% lidocaine (lidocaine group) or normal saline solution (saline group) was injected. In the lidocaine group, data were recorded immediately before SGB and at the time when the maximal change in the common carotid arterial blood flow was observed after SGB. In the saline group, data were recorded immediately before SGB and 3 minutes after SGB. Observed variables were blood pressure, heart rate, common carotid arterial blood flow, tongue mucosal blood flow, mandibular bone marrow blood flow (BBF), masseter muscle blood flow (MBF), quadriceps muscle blood flow, liver blood flow, and renal blood flow.

RESULTS

Common carotid arterial blood flow, tongue mucosal blood flow, BBF, and MBF on the block side were increased, whereas BBF and MBF on the nonblock side and quadriceps muscle blood flow, liver blood flow, and renal blood flow were decreased after SGB in the lidocaine group.

CONCLUSIONS

These results indicate that lower limb and visceral blood flow as well as blood flow on the nonblock side are redistributed to the block side after SGB. Redistribution from peripheral tissue may have a more important role than that of visceral blood flow redistribution after SGB.

摘要

背景与目的

本研究旨在比较星状神经节阻滞(SGB)前后不同部位的组织血流,并探讨 SGB 后组织血流的再分布情况。

方法

我们研究了 16 只雄性日本白兔。对于 SGB,将 26 号针头的尖端置于颈椎的左侧横突,环状软骨后 1 至 2 毫米处。在利多卡因组中,在 SGB 前和 SGB 后观察到颈总动脉血流最大变化时记录数据。在生理盐水组中,在 SGB 前和 SGB 后 3 分钟记录数据。观察变量包括血压、心率、颈总动脉血流、舌黏膜血流、下颌骨骨髓血流(BBF)、咬肌血流(MBF)、股四头肌血流、肝血流和肾血流。

结果

利多卡因组 SGB 后,阻塞侧颈总动脉血流、舌黏膜血流、BBF 和 MBF 增加,而非阻塞侧 BBF 和 MBF 以及股四头肌血流、肝血流和肾血流减少。

结论

这些结果表明,SGB 后下肢和内脏血流以及非阻塞侧血流重新分布到阻塞侧。外周组织的再分配可能比 SGB 后内脏血流的再分配更重要。

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