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依那西普治疗相关的急性葡萄膜炎:一例病例报告及文献复习。

Etanercept therapy-associated acute uveitis: a case report and literature review.

机构信息

Department of Nephrology and Rheumatology, The Sixth People's Hospital attached to Shanghai Jiaotong University, China.

出版信息

Clin Exp Rheumatol. 2009 Sep-Oct;27(5):838-9.

Abstract

A female patient diagnosed with ankylosing spondylitis experienced a new onset acute iritis following the initiation of etanercept therapy and recurrent episodes of iritis continues during the treatment of etanercept. Etanercept-associated iritis was suspected. Anti-TNF therapies can alleviate uveitis in some studies, but in some other anecdotal reports etanercept is considered as the main cause of uveitis. A literature review is presented below. For clinicians, more attention must be paid to the potential association between uveitis or iritis and etanercept, and more careful surveillance of patients under etanercept treatment is necessary.

摘要

一位被诊断患有强直性脊柱炎的女性患者在接受依那西普治疗后出现新发急性虹膜炎,并且在依那西普治疗期间虹膜炎反复发作。疑似与依那西普相关的虹膜炎。一些研究表明,抗 TNF 治疗可缓解葡萄膜炎,但在一些其他的偶发报告中,依那西普被认为是葡萄膜炎的主要原因。现对文献进行回顾。对于临床医生来说,必须更加注意葡萄膜炎或虹膜炎与依那西普之间的潜在关联,并在依那西普治疗下更加仔细地监测患者。

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