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依那西普治疗相关的急性葡萄膜炎:一例病例报告及文献复习。

Etanercept therapy-associated acute uveitis: a case report and literature review.

机构信息

Department of Nephrology and Rheumatology, The Sixth People's Hospital attached to Shanghai Jiaotong University, China.

出版信息

Clin Exp Rheumatol. 2009 Sep-Oct;27(5):838-9.

PMID:19917170
Abstract

A female patient diagnosed with ankylosing spondylitis experienced a new onset acute iritis following the initiation of etanercept therapy and recurrent episodes of iritis continues during the treatment of etanercept. Etanercept-associated iritis was suspected. Anti-TNF therapies can alleviate uveitis in some studies, but in some other anecdotal reports etanercept is considered as the main cause of uveitis. A literature review is presented below. For clinicians, more attention must be paid to the potential association between uveitis or iritis and etanercept, and more careful surveillance of patients under etanercept treatment is necessary.

摘要

一位被诊断患有强直性脊柱炎的女性患者在接受依那西普治疗后出现新发急性虹膜炎,并且在依那西普治疗期间虹膜炎反复发作。疑似与依那西普相关的虹膜炎。一些研究表明,抗 TNF 治疗可缓解葡萄膜炎,但在一些其他的偶发报告中,依那西普被认为是葡萄膜炎的主要原因。现对文献进行回顾。对于临床医生来说,必须更加注意葡萄膜炎或虹膜炎与依那西普之间的潜在关联,并在依那西普治疗下更加仔细地监测患者。

相似文献

1
Etanercept therapy-associated acute uveitis: a case report and literature review.依那西普治疗相关的急性葡萄膜炎:一例病例报告及文献复习。
Clin Exp Rheumatol. 2009 Sep-Oct;27(5):838-9.
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[Onset of Crohn's disease induced by etanercept therapy: a case report].[英夫利昔单抗治疗诱发克罗恩病发病:一例报告]
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Reversible heart failure in a patient receiving etanercept for ankylosing spondylitis.接受依那西普治疗强直性脊柱炎的患者出现可逆性心力衰竭。
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New onset of Crohn's disease during treatment of active ankylosing spondylitis with etanercept.在用依那西普治疗活动性强直性脊柱炎期间新发克罗恩病。
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Analysis of uveitis rates across all etanercept ankylosing spondylitis clinical trials.分析所有依那西普治疗强直性脊柱炎临床试验中的葡萄膜炎发生率。
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Sustained efficacy and safety, including patient-reported outcomes, with etanercept treatment over 5 years in patients with ankylosing spondylitis.依那西普治疗强直性脊柱炎患者 5 年以上的持续疗效和安全性,包括患者报告的结局。
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Effect of etanercept on iritis in patients with ankylosing spondylitis.依那西普对强直性脊柱炎患者虹膜炎的疗效
Arthritis Rheum. 2004 Nov;50(11):3736-7. doi: 10.1002/art.20754.

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An Observational Study in the Real Clinical Practice of the Treatment of Noninfectious Uveitis.
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Serious Adverse Events Associated with Anti-Tumor Necrosis Factor Alpha Agents in Pediatric-Onset Inflammatory Bowel Disease and Juvenile Idiopathic Arthritis in A Real-Life Setting.在实际临床环境中,与抗肿瘤坏死因子α制剂相关的严重不良事件在儿童期起病的炎症性肠病和幼年特发性关节炎中的情况
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Disease status, reasons for discontinuation and adverse events in 1038 Italian children with juvenile idiopathic arthritis treated with etanercept.1038名接受依那西普治疗的意大利幼年特发性关节炎儿童的疾病状况、停药原因及不良事件
Pediatr Rheumatol Online J. 2016 Dec 20;14(1):68. doi: 10.1186/s12969-016-0126-0.
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Risk factors of uveitis in ankylosing spondylitis: An observational study.强直性脊柱炎葡萄膜炎的危险因素:一项观察性研究。
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