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主动脉感染性动脉瘤的诊断与管理

Diagnosis and management of aortic mycotic aneurysms.

作者信息

Leon Luis R, Mills Joseph L

机构信息

Department of Vascular Surgery, Tucson Medical Center, Tucson, AZ, USA.

出版信息

Vasc Endovascular Surg. 2010 Jan;44(1):5-13. doi: 10.1177/1538574409344225. Epub 2009 Nov 16.

Abstract

We reviewed all papers most recently reported in the literature (January-December 2008) with regard to infected arterial aneurysms (IAAs) affecting the aorta. Most of the recently reported knowledge is limited to case reports and small series of aortic mycotic aneurysms. Most patients are elderly men and have comorbidities at presentation. Aneurysms were most commonly associated to Salmonella and Staphylococcus. However, several cases of aortic IAAs caused by atypical pathogens were also reported, likely due to an increase in immunosuppressive illnesses, increased life expectancy, improved diagnostic methods, and increasing medical awareness. Open surgical therapy of IAAs remains the gold standard. Some have reported successful outcomes with endovascular methodologies for patients medically compromised or for particular challenging clinical or anatomical scenarios. However, at this time, conclusive evidence is lacking and it should be in general considered a bridge to open repair. The latter should be planned at the earliest possible, when medically permissible.

摘要

我们回顾了文献中最近报道的(2008年1月至12月)所有关于累及主动脉的感染性动脉瘤(IAA)的论文。最近报道的大多数知识仅限于病例报告和少量主动脉真菌性动脉瘤系列研究。大多数患者为老年男性,就诊时伴有合并症。动脉瘤最常与沙门氏菌和葡萄球菌相关。然而,也报道了几例由非典型病原体引起的主动脉IAA病例,这可能归因于免疫抑制性疾病的增加、预期寿命的延长、诊断方法的改进以及医学认知的提高。IAA的开放手术治疗仍然是金标准。一些人报告了对于病情严重或处于特殊具有挑战性的临床或解剖学情况的患者,采用血管内治疗方法取得了成功结果。然而,目前缺乏确凿证据,一般应将其视为通向开放修复的桥梁。在医学允许的情况下,应尽早计划进行后者(开放修复)。

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