Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Diabetes Care. 2010 Feb;33(2):275-7. doi: 10.2337/dc09-1021. Epub 2009 Nov 16.
To validate a low-cost tool for identifying diabetic patients in rural areas of Latin America.
A regression equation incorporating postprandial time and a random plasma glucose was used to screen 800 adults in Honduras. Patients with a probability of diabetes of > or =20% were asked to return for a fasting plasma glucose (FPG). A random fifth of those with a screener-based probability of diabetes <20% were also asked to return for follow-up. The gold standard was an FPG > or =126 mg/dl.
The screener had very good test characteristics (area under the receiver operating characteristic curve = 0.89). Using the screening criterion of > or =0.42, the equation had a sensitivity of 74.1% and specificity of 97.2%.
This screener is a valid measure of diabetes risk in Honduras and could be used to identify diabetic patients in poor clinics in Latin America.
验证一种用于识别拉丁美洲农村地区糖尿病患者的低成本工具。
采用包含餐后时间和随机血浆葡萄糖的回归方程对洪都拉斯的 800 名成年人进行筛查。对糖尿病概率>或=20%的患者进行空腹血浆葡萄糖（FPG）检测。对基于筛查器的糖尿病概率<20%的随机五分之一患者也要求进行随访。金标准为 FPG>或=126mg/dl。
该筛查器具有很好的测试特征（受试者工作特征曲线下面积=0.89）。使用>或=0.42 的筛查标准，该方程的敏感性为 74.1%，特异性为 97.2%。
该筛查器是洪都拉斯糖尿病风险的有效衡量标准，可用于识别拉丁美洲贫困诊所中的糖尿病患者。
