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儿童患者中爆发的全北界型土拉菌病。

An outbreak of holarctica-type tularemia in pediatric patients.

机构信息

Department of Pediatrics, University of Oulu, Oulu, Finland.

出版信息

Pediatr Infect Dis J. 2010 Feb;29(2):160-2. doi: 10.1097/INF.0b013e3181b9a6b4.

Abstract

BACKGROUND

Holarctica-type tularemia is endemic in the Northern Hemisphere. Despite recurrent epidemics tularemia is not well known in children and the pediatric cases are often misdiagnosed.

METHODS

An outbreak of holarctica-type tularemia occurred in the Oulu region of Northern Finland in late summer/early August 2007. We collected prospectively data on all the cases of children diagnosed and treated for tularemia at the Department of Pediatrics, Oulu University Hospital, during the epidemic from July through September 2007.

RESULTS

Fifty patients were confirmed as having tularemia. All the cases appeared in a relatively small part of the Oulu region and almost all came from an area about 40 km in diameter where the annual incidence rate was high (342/100,000). Ulceroglandular tularemia was recorded in 47 of the 50 cases and secondary skin manifestations in half of the cases.

CONCLUSIONS

Tularemia caused by holarctica-type bacteria is a relatively mild infection, but symptoms are protracted in children and an epidemic consumes considerable health care resources.

摘要

背景

极地型兔热病在北半球流行。尽管反复出现流行,但儿童对该病的了解甚少,儿科病例常被误诊。

方法

2007 年夏末/初秋,芬兰北部的奥卢地区爆发了极地型兔热病。我们前瞻性地收集了 2007 年 7 月至 9 月期间在奥卢大学医院儿科部门诊断和治疗的所有儿童兔热病病例的数据。

结果

50 名患者被确诊为兔热病。所有病例都出现在奥卢地区的一个相对较小的区域,几乎都来自一个直径约 40 公里的区域,该区域的年发病率很高(342/100,000)。50 例中有 47 例为溃疡腺型兔热病,有一半病例出现继发性皮肤表现。

结论

由极地型细菌引起的兔热病是一种相对较轻的感染,但在儿童中症状持续时间较长,且疫情会消耗大量的医疗资源。

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