Batista Raquel Ribeiro, Marchiori Edson, Takayassu Tatiana Chinem, Cabral Fernanda Caseira, Cabral Rafael Ferracini, Zanetti Gláucia
Service of Diagnostic Radiology, Clementino Fraga Filho Universitary Hospital, Rua Prof. Rodolpho Paulo Rocco, 225. CEP 21.941.913. Cidade Universitária. Rio de Janeiro, Brazil.
Cases J. 2009 Sep 10;2:9045. doi: 10.4076/1757-1626-2-9045.
Renal cell carcinoma accounts for 85% of all solid renal tumors in adults. Nearly one quarter of patients has distant metastasis at presentation while another 50% develop metastasis during follow-up. A small percentage of these are solitary metastasis. We report here a case of solitary bone sternal metastasis as an initial presentation of clear-cell renal cell carcinoma in a 56-year-old woman. The prognosis for patients with metastasized renal cell carcinoma is poor; treatment of metastasis is usually palliative and designed to provide comfort and pain relief. Palliative nephrectomy may be considered for control of symptoms. Radical nephrectomy associated with metastatic bone tumor resection is being tested to improve functional status and survival, especially when metastasis involves supporting bones.
肾细胞癌占成人所有实性肾肿瘤的85%。近四分之一的患者在初诊时已有远处转移，另有50%的患者在随访期间发生转移。其中一小部分为孤立性转移。我们在此报告一例56岁女性，以孤立性胸骨骨转移作为透明细胞肾细胞癌的首发表现。转移性肾细胞癌患者的预后较差；转移的治疗通常是姑息性的，旨在缓解症状和减轻疼痛。可考虑行姑息性肾切除术以控制症状。目前正在试验将根治性肾切除术与转移性骨肿瘤切除术相结合，以改善功能状态和提高生存率，特别是当转移累及承重骨时。
