Kadam Umesh T
Arthritis Research Campaign National Primary Care Centre, Keele University Staffordshire ST5 5BG UK.
Cases J. 2009 Aug 20;2:8542. doi: 10.4076/1757-1626-2-8542.
Older populations are more at risk of problems such as temporal arteritis or polymyalgia rheumatica, and these conditions are often first diagnosed in general practice, with usual ongoing care and long-term treatment with oral steroids. These inflammatory conditions are also potential risk factors for other complicating presentations such as transient ischaemic attacks, but the precise comorbid links and how these might influence clinical management in general practice are unclear.
An 82-year-Caucasian woman living alone requested a home visit after a single episode of speech disturbance and disorientation which lasted 15 minutes. This occurred 2 weeks after cessation of her oral prednisolone for temporal arteritis, which was clinically diagnosed in 2006 and later confirmed by a biopsy. She also had a past medical history of ischaemic heart disease based on symptom presentation and an abnormal ECG in October 2005, but no other relevant risk factors for cardiovascular disease.
Transient ischaemic attack is an alternative presentation or complication of an inflammatory disease such as temporal arteritis. The clinical implications of this case relate to the assessment of comorbid risk in TA and in tailoring the drug treatment. In using prednisolone treatments in such patients, general practitioners will need to carefully titrate drug doses and the duration of treatment to prevent complications. Clear evidence for the precise type of management remains to be established.
老年人群更容易患颞动脉炎或风湿性多肌痛等疾病,这些病症通常首先在全科医疗中被诊断出来,随后接受常规的持续护理以及口服类固醇的长期治疗。这些炎症性疾病也是其他并发症(如短暂性脑缺血发作)的潜在危险因素,但确切的共病关联以及它们如何影响全科医疗中的临床管理尚不清楚。
一位82岁独居的白人女性在经历了一次持续15分钟的言语障碍和定向障碍后要求进行家访。这发生在她因颞动脉炎停用口服泼尼松龙2周后,颞动脉炎于2006年临床诊断,后来经活检确诊。根据症状表现和2005年10月异常的心电图,她还有缺血性心脏病的病史,但没有其他心血管疾病的相关危险因素。
短暂性脑缺血发作是颞动脉炎等炎症性疾病的另一种表现形式或并发症。该病例的临床意义涉及颞动脉炎中共病风险的评估以及药物治疗的调整。在此类患者中使用泼尼松龙治疗时,全科医生需要仔细调整药物剂量和治疗持续时间以预防并发症。关于确切管理类型的确凿证据仍有待确立。