Bengtsson B A, Malmvall B E
Arthritis Rheum. 1981 Jul;24(7):899-904. doi: 10.1002/art.1780240706.
During a period of three years in Göteborg, Sweden, 126 cases of giant cell arteritis (GCA) were diagnosed. Histologic evidence of arteritis was found on temporal artery biopsy in 74 (59%). The total annual incidence of GCA was calculated to be 9.3 per 100,000 inhabitants. In the age group over 50, incidence was 28.6 per 100,000. For histologically proven GCA, the incidence was 5.5 per 100,000 of the total population. The corresponding figure in the age group over 50 was 16.8 per 100,000. Twenty-six patients (21%) had a clinical presentation of temporal arteritis, and 23 (18%) had a combined picture of temporal arteritis and polymyalgia rheumatica (PMR). Sixty-seven (53%) had the PMR syndrome without any temporal symptoms, and 10 patients (8%) had a "silent" presentation with only general symptoms. The PMR syndrome was more common among women with GCA (79%) than among men (56%). The group of patients without muscular symptoms contained an equal number of men and women. Eye complications were seen in 15 patients (12%). In 6, the ocular symptoms were transient, while 9 suffered from permanent loss of vision. In 3 of these patients, temporal artery biopsy revealed no evidence of arteritis, and 5 had no clinical signs of localized temporal arteritis.
在瑞典哥德堡的三年时间里，共诊断出126例巨细胞动脉炎（GCA）。74例（59%）颞动脉活检发现动脉炎的组织学证据。GCA的年总发病率经计算为每10万居民中有9.3例。在50岁以上年龄组中，发病率为每10万居民中有28.6例。对于经组织学证实的GCA，在总人口中的发病率为每10万居民中有5.5例。在年龄组50岁以上的相应数字为每10万居民中有16.8例。26例患者（21%）有颞动脉炎的临床表现，23例（18%）有颞动脉炎和风湿性多肌痛（PMR）的合并表现。67例（53%）有PMR综合征但无任何颞部症状，10例患者（8%）有仅伴有全身症状的“无症状”表现。GCA患者中，PMR综合征在女性（79%）中比在男性（56%）中更常见。无肌肉症状的患者组中男女数量相等。15例患者（12%）出现眼部并发症。其中6例眼部症状为短暂性，而9例视力永久性丧失。在这些患者中，3例颞动脉活检未发现动脉炎证据，5例无局限性颞动脉炎的临床体征。
