Imam Ibrahim, Edwards Simon, Hanemann C Oliver
Neurology Department, Torbay Hospital, Torquay TQ2 7AA, UK.
Cases J. 2009 Sep 8;2:7952. doi: 10.4076/1757-1626-2-7952.
We present a 37-year-old male subject who presented with burning sensations in his hands and feet with generalised twitching of his limbs, trunk and face. His symptoms developed 2 weeks after an upper respiratory tract infection. There was associated facial flushing and disturbed night sleep but no memory impairment or generalised sweating. Examination showed generalised myokymia and fasciculations and electromyography revealed widespread continuous semi-rhythmic doublets and triplets of low frequency with interspersed silent periods. Anti voltage gated potassium channel antibodies, antinuclear antibodies, anti-acetylcholine receptor antibodies and the anti-neuronal antibodies anti Hu, anti Yo and anti Ri were all negative. His symptoms improved slightly on lamotrigine and amitriptyline.
我们报告一名37岁男性患者，其双手和双脚有烧灼感，伴有四肢、躯干和面部的全身性抽搐。他的症状在上呼吸道感染后2周出现。伴有面部潮红和睡眠障碍，但无记忆障碍或全身性出汗。检查发现全身性肌束震颤和肌束颤动，肌电图显示广泛的连续低频半节律性双峰和三峰，其间有间歇期。抗电压门控钾通道抗体、抗核抗体、抗乙酰胆碱受体抗体以及抗神经元抗体抗Hu、抗Yo和抗Ri均为阴性。他的症状在服用拉莫三嗪和阿米替林后略有改善。
