Asadi Mehrnaz, Rokni-Yazdi Hadi, Salehinia Farahnaz, Allameh Farshad S
Department of General Internal Medicine, Imam Khomeini Hospital, Keshavarz Boulevard, Medical Sciences/Tehran University,Tehran, Iran.
Cases J. 2009 Sep 11;2:7805. doi: 10.4076/1757-1626-2-7805.
One of the rare manifestations of systemic neoplasia is intramedullary spinal cord metastasis that causes serious diagnostic and therapeutic dilemma. It has been very rarely reported as the initial manifestation of carcinoma. This is report of a metastatic renal cell carcinoma initially presented with intramedullary spinal cord lesion, to our knowledge there are few similar reports in literature.
We report a 51-year-old Iranian woman who presented with back pain and paraparesis. MR imaging study of her spine showed an enhancing cystic lesion at the level of conus medullaris. Despite detailed investigation, no specific aetiology was found till a bone scan obtained to evaluate an agonizing pain on the dorsum of the left hand revealed photon deficient area within the left kidney in addition to oseoblastic bony lesions. After thorough imaging investigation she underwent radical nephrectomy which confirmed renal cell carcinoma.
Considering the prevalence of cancer, it is imperative that clinicians be mindful of occult carcinoma as the cause of suspicious intramedullary spinal cord lesion.
系统性肿瘤的罕见表现之一是脊髓髓内转移,这会导致严重的诊断和治疗困境。作为癌症的初始表现,这种情况很少被报道。据我们所知,本文报道了一例以脊髓髓内病变为首发表现的转移性肾细胞癌,文献中鲜有类似报道。
我们报告一名51岁的伊朗女性,她出现背痛和双下肢轻瘫。其脊柱的磁共振成像研究显示圆锥水平有一个强化的囊性病变。尽管进行了详细检查,但直到为评估左手背部的剧痛而进行骨扫描时,除了成骨骨性病变外,还发现左肾内有光子缺乏区,才发现具体病因。经过全面的影像学检查后,她接受了根治性肾切除术,病理证实为肾细胞癌。
鉴于癌症的发病率,临床医生必须注意隐匿性癌症可能是可疑脊髓髓内病变的病因。