Porto Alegre Hospital de Clínicas, Universidade Federal do Rio Grande do Sul - UFRGS, Rio Grande do Sul Federal University - School of Medicine, Porto Alegre, Brazil.
J Bras Pneumol. 2009 Oct;35(10):966-72. doi: 10.1590/s1806-37132009001000004.
To determine the relationship between nutritional status and dietary intake in patients with cystic fibrosis.
Cross-sectional study involving 85 cystic fibrosis patients between 6 and 18 years of age. Dietary intake was evaluated by the 3-day diet record (weighing the food consumed). The outcome measures were the following nutritional status indicators: weight/height (W/H%) percentage, body mass index (BMI) percentiles, Z score for weight/age (W/A), Z score for height/age (H/A) and percentage of dietary intake compared with the Recommended Dietary Allowance (RDA).
The prevalence of well-nourished patients was 77.7%, using BMI above the 25th percentile as the cut-off value, and the W/H% was above 90% in 83.5%. The mean dietary intake, evaluated in 82 patients, was 124.5% of the RDA. In the univariate logistic regression analyses, we found a significant association between the independent variable calorie intake and the Z score for W/A. The multivariate analysis, based on the Z score for H/A and adjusted for FEV1, methicillin-resistant Staphylococcus aureus colonization and number of hospitalizations, demonstrated that a 1% increase in the calorie intake decreases the chance of having short stature by 2% (OR: 0.98; 95% CI: 0.96-1.00). Maternal level of education showed a borderline association (p = 0.054).
The prevalence of malnutrition was low in this sample of patients. The study model demonstrated an association between dietary intake and nutritional status. Dietary intake was a predictive factor of statural growth in patients with cystic fibrosis.
确定囊性纤维化患者的营养状况与饮食摄入之间的关系。
这是一项涉及 85 名 6 至 18 岁囊性纤维化患者的横断面研究。通过 3 天饮食记录(称重所消耗的食物)评估饮食摄入。评估的营养状况指标包括:体重/身高(W/H%)百分比、体重指数(BMI)百分位数、体重/年龄(W/A)Z 评分、身高/年龄(H/A)Z 评分以及与推荐膳食摄入量(RDA)相比的饮食摄入量百分比。
采用 BMI 超过第 25 百分位数作为截断值,营养良好的患者患病率为 77.7%,W/H%超过 90%的患者为 83.5%。对 82 名患者进行了平均饮食摄入量评估,结果为 RDA 的 124.5%。在单变量逻辑回归分析中,我们发现独立变量卡路里摄入量与 W/A 的 Z 评分之间存在显著关联。基于 H/A 的 Z 评分并调整 FEV1、耐甲氧西林金黄色葡萄球菌定植和住院次数的多变量分析表明,卡路里摄入量增加 1%,矮小的机会就会降低 2%(OR:0.98;95%CI:0.96-1.00)。母亲的教育水平与结果呈边缘相关(p = 0.054)。
在本研究样本中,营养不良的患病率较低。研究模型表明饮食摄入与营养状况之间存在关联。饮食摄入是囊性纤维化患者身高增长的预测因素。