Leonhardt H, Arntz H R, Klemens U H
Atherosclerosis. 1977 Sep;28(1):29-40. doi: 10.1016/0021-9150(77)90196-4.
Using an Ubbelohde capillary viscometer, viscosity was determined in the plasma of 39 patients with a primary hyperlipoproteinaemia (type IIa, n=13; type IV, n=12; type IIb, n=14), in isolated lipoprotein fractions as well as in sera which differed only in their lipoprotein concentration. Plasma viscosity of the patients with hyperlipoproteinaemia was compared to that of a normolipidaemic control group and correlated with the lipid fractions characteristic of the different hyperlipoproteinaemia types. Plasma viscosity in types IIa, IV and IIb was found to be significantly higher than in the control group. Of the different hyperlipoproteinaemia types, IIa exhibited the lowest and IIb the highest plasma viscosity levels. The elevation of plasma viscosity was correlated with the concentration of lipoproteins (lipid fractions). In viscosity measurements of sera which varied only in lipoprotein concentrations, a correlation between the increase of viscosity and lipoprotein concentration as well as a greater efficiency of VLDL fractions was observed, similar to the viscosity results from isolated lipoproteins.
使用乌氏毛细管粘度计，测定了39例原发性高脂血症患者（IIa型，n = 13；IV型，n = 12；IIb型，n = 14）血浆、分离的脂蛋白组分以及仅脂蛋白浓度不同的血清的粘度。将高脂血症患者的血浆粘度与血脂正常的对照组进行比较，并与不同类型高脂血症的特征性脂质组分相关联。发现IIa型、IV型和IIb型患者的血浆粘度显著高于对照组。在不同类型的高脂血症中，IIa型血浆粘度最低，IIb型最高。血浆粘度的升高与脂蛋白（脂质组分）浓度相关。在仅脂蛋白浓度不同的血清粘度测量中，观察到粘度增加与脂蛋白浓度之间的相关性以及极低密度脂蛋白组分的更大作用，这与分离脂蛋白的粘度结果相似。
