De Schepper J, Derde M P, Van den Broeck M, Piepsz A, Jonckheer M H
Department of Pediatrics, Akademisch Ziekenhuis, Vrije Universiteit Brussel, Belgium.
J Nucl Med. 1991 Feb;32(2):216-20.
In 136 normal growing children between the ages of 1 and 18 yr, bone mineral content (BMC) at the level of the lumbar spine (L2-L4) was determined with a commercial dual-photon absorptiometer. BMC was calculated as BML (BMC per unit length) and BMD (BMC per unit surface). The mean lumbar spine BML of the studied children (2.53 +/- 0.86 gHA/cm) was significantly lower than the spinal mineral content of adults (4.26 +/- 0.57 gHA/cm). No sex difference existed in lumbar spine BMC. BML as well as BMD were highly dependent on age, body height, and body weight. During the prepubertal years, BML and BMD increased in a fairly rectilinear pattern. During puberty, BMC increased more rapidly: 40% for BMD and 77% for BML. For the entire group, the increase in BMC with age, height, and weight was best predicted by an exponential regression line analysis.
在136名年龄在1至18岁之间正常生长的儿童中,使用商用双能光子吸收仪测定腰椎(L2-L4)水平的骨矿物质含量(BMC)。BMC计算为BML(每单位长度的BMC)和BMD(每单位面积的BMC)。研究儿童的平均腰椎BML(2.53±0.86 gHA/cm)显著低于成年人的脊柱矿物质含量(4.26±0.57 gHA/cm)。腰椎BMC不存在性别差异。BML以及BMD高度依赖于年龄、身高和体重。在青春期前的几年里,BML和BMD以相当直线的模式增加。在青春期,BMC增加得更快:BMD增加40%,BML增加77%。对于整个组,通过指数回归线分析可以最好地预测BMC随年龄、身高和体重的增加。