Yurgin Nicole Rae, Boye Kristina Secnik, Dilla Tatiana, Suriñach Núria Lara, Llach Xavier Badia
Eli Lilly and Company, Indianapolis, IN, USA;
Patient Prefer Adherence. 2008 Feb 2;2:87-95.
The objective of this study was to assess current treatment patterns, blood glucose test strip usage, and treatment compliance in patients with type 2 diabetes mellitus (T2DM) in primary care centers in Spain, and to assess factors related to glycemic control. We conducted a retrospective chart review of patients with T2DM and measured treatment compliance using the Morisky-Green questionnaire. 294 patients were included in the study from a population of patients attending 30 primary care centers throughout Spain. Results showed that the majority of patients were treated with oral monotherapy (36%) and oral combination therapy (35%). Less than half of the patients had good glycemic control (HbA(1c) </= 6.5%). Half of the patients treated pharmacologically reported good compliance with treatment. Logistic regression analyses performed to identify factors associated with glycemic control showed that high body mass index (BMI) and poor compliance were the strongest predictors of poor HbA(1c) control (OR: 2.198 and 1.789, respectively, p < 0.05). In conclusion, in the course of managing diabetes, physicians and patients should attempt to improve compliance and lower BMI, which could lead to better glycemic control.
本研究的目的是评估西班牙初级保健中心2型糖尿病(T2DM)患者的当前治疗模式、血糖试纸使用情况和治疗依从性,并评估与血糖控制相关的因素。我们对T2DM患者进行了回顾性病历审查,并使用Morisky - Green问卷测量治疗依从性。研究纳入了来自西班牙30个初级保健中心就诊患者群体中的294例患者。结果显示,大多数患者接受口服单药治疗(36%)和口服联合治疗(35%)。不到一半的患者血糖控制良好(糖化血红蛋白[HbA(1c)]≤6.5%)。接受药物治疗的患者中有一半报告治疗依从性良好。为确定与血糖控制相关因素而进行的逻辑回归分析表明,高体重指数(BMI)和依从性差是HbA(1c)控制不佳的最强预测因素(比值比分别为2.198和1.789,p<0.05)。总之,在糖尿病管理过程中,医生和患者应努力提高依从性并降低BMI,这可能会带来更好的血糖控制。