Experimental and Biological Psychology, Philipps-University Marburg, Germany.
Neurosci Lett. 2010 Jan 14;468(3):339-43. doi: 10.1016/j.neulet.2009.11.028. Epub 2009 Nov 14.
To date, much is known about the neural mechanisms underlying working-memory (WM) maintenance and long-term-memory (LTM) encoding. However, these topics have typically been examined in isolation, and little is known about how these processes might interact. Here, we investigated whether EEG oscillations arising specifically during the delay of a delayed matching-to-sample task reflect successful LTM encoding. Given previous findings of increased alpha and theta power with increasing WM load, together with the assumption that successful memory encoding involves processes that are similar to those that are invoked by increasing WM load, alpha and theta power should be higher for subsequently remembered stimuli. Consistent with this assumption, we found stronger alpha power for subsequently remembered stimuli over occipital-to-parietal scalp sites. Furthermore, stronger theta power was found for subsequently remembered stimuli over parietal-to-central electrodes. These results support the idea that alpha and theta oscillations modulate successful LTM encoding.
迄今为止，人们对工作记忆（WM）维持和长期记忆（LTM）编码的神经机制有了很多了解。然而，这些主题通常是单独研究的，对于这些过程如何相互作用知之甚少。在这里，我们研究了在延迟匹配样本任务的延迟期间特定出现的 EEG 振荡是否反映了成功的 LTM 编码。鉴于以前发现随着 WM 负荷的增加，α波和θ波的功率增加，并且假设成功的记忆编码涉及与增加 WM 负荷所调用的过程相似的过程，因此对于随后被记住的刺激，α波和θ波的功率应该更高。与这一假设一致，我们发现枕部到顶叶头皮区域的随后被记住的刺激的α波功率更强。此外，在顶叶到中央电极上发现了随后被记住的刺激的更强的θ波功率。这些结果支持α波和θ波振荡调节成功的 LTM 编码的观点。
