Department of Pharmacy, University Health System, San Antonio, Texas 78229, USA.
J Clin Microbiol. 2010 Jan;48(1):298-9. doi: 10.1128/JCM.01875-09. Epub 2009 Nov 18.
One hundred four Enterobacter isolates were tested by standard CLSI disk diffusion methods for detecting extended-spectrum beta-lactamases (ESBLs) and with cefepime-clavulanate disk combinations. SHV-12 was produced by 8.7% of isolates. The cefepime-clavulanate combination provided 88% sensitivity and 91% specificity for the detection of SHV-12 ESBL.
经标准 CLSI 纸片扩散法检测,104 株肠杆菌属分离株对产超广谱β-内酰胺酶(ESBLs)和头孢吡肟-克拉维酸纸片组合进行了检测。8.7%的分离株产生 SHV-12。头孢吡肟-克拉维酸组合对 SHV-12 ESBL 的检测具有 88%的敏感性和 91%的特异性。