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Septic acute kidney injury and tubular apoptosis: never a Lone Ranger.

作者信息

Joannes-Boyau Olivier, Honoré Patrick M, Boer Willem, Rose Thomas

出版信息

Intensive Care Med. 2010 Mar;36(3):385-8. doi: 10.1007/s00134-009-1725-8.

DOI:10.1007/s00134-009-1725-8
PMID:19924394
Abstract
摘要

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Distinct pathophysiologic mechanisms of septic acute kidney injury: role of immune suppression and renal tubular cell apoptosis in murine model of septic acute kidney injury.脓毒症急性肾损伤的不同病理生理机制:免疫抑制和肾小管细胞凋亡在脓毒症急性肾损伤小鼠模型中的作用。
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A unified theory of sepsis-induced acute kidney injury: inflammation, microcirculatory dysfunction, bioenergetics, and the tubular cell adaptation to injury.脓毒症相关性急性肾损伤的统一理论:炎症、微循环功能障碍、生物能量学以及肾小管细胞损伤适应。
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Tubular cell damage in acute renal failure-apoptosis, necrosis, or both.急性肾衰竭时的肾小管细胞损伤——凋亡、坏死,或两者皆有。
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Circulating plasma factors induce tubular and glomerular alterations in septic burns patients.循环血浆因子可导致脓毒症烧伤患者出现肾小管和肾小球改变。
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Neferine Attenuates Acute Kidney Injury by Inhibiting NF-κB Signaling and Upregulating Klotho Expression.莲心碱通过抑制NF-κB信号通路和上调Klotho表达减轻急性肾损伤。
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本文引用的文献

1
Intensity of continuous renal-replacement therapy in critically ill patients.危重症患者持续肾脏替代治疗的强度
N Engl J Med. 2009 Oct 22;361(17):1627-38. doi: 10.1056/NEJMoa0902413.
2
Epidemiology of septic acute kidney injury.脓毒症相关性急性肾损伤的流行病学。
Curr Drug Targets. 2009 Dec;10(12):1169-78. doi: 10.2174/138945009789753183.
3
Intensity of renal replacement therapy in acute kidney injury: perspective from within the Acute Renal Failure Trial Network Study.急性肾损伤肾脏替代治疗的强度:来自急性肾损伤临床试验网络研究的视角。
淫羊藿苷 B 通过激活 IGF 通路来预防急性肾损伤。
Molecules. 2019 Oct 28;24(21):3876. doi: 10.3390/molecules24213876.
4
Xenon Protects Against Septic Acute Kidney Injury via miR-21 Target Signaling Pathway.氙气通过miR-21靶向信号通路预防脓毒症急性肾损伤。
Crit Care Med. 2015 Jul;43(7):e250-9. doi: 10.1097/CCM.0000000000001001.
5
Septic AKI in ICU patients. diagnosis, pathophysiology, and treatment type, dosing, and timing: a comprehensive review of recent and future developments.ICU 患者的脓毒症急性肾损伤。诊断、病理生理学、治疗类型、剂量和时机:近期和未来发展的综合回顾。
Ann Intensive Care. 2011 Aug 9;1(1):32. doi: 10.1186/2110-5820-1-32.
6
Apoptosis and acute kidney injury.细胞凋亡与急性肾损伤。
Kidney Int. 2011 Jul;80(1):29-40. doi: 10.1038/ki.2011.120. Epub 2011 May 11.
7
Sepsis and AKI: more complex than just a simple question of chicken and egg.脓毒症与急性肾损伤:比简单的因果关系问题更为复杂。
Intensive Care Med. 2011 Feb;37(2):186-9. doi: 10.1007/s00134-010-2097-9. Epub 2010 Dec 9.
Crit Care. 2009;13(4):310. doi: 10.1186/cc7901. Epub 2009 Aug 11.
4
Ghrelin protects mice against endotoxemia-induced acute kidney injury.胃饥饿素可保护小鼠免受内毒素血症诱导的急性肾损伤。
Am J Physiol Renal Physiol. 2009 Oct;297(4):F1032-7. doi: 10.1152/ajprenal.00044.2009. Epub 2009 Jul 22.
5
Comparison of cardiac, hepatic, and renal effects of arginine vasopressin and noradrenaline during porcine fecal peritonitis: a randomized controlled trial.比较精氨酸加压素和去甲肾上腺素在猪粪性腹膜炎期间对心脏、肝脏和肾脏的影响:一项随机对照试验。
Crit Care. 2009;13(4):R113. doi: 10.1186/cc7959. Epub 2009 Jul 10.
6
Continuous hemofiltration in 2009: what is new for clinicians regarding pathophysiology, preferred technique and recommended dose?2009年的连续性血液滤过:就病理生理学、首选技术和推荐剂量而言,临床医生需要了解哪些新内容?
Blood Purif. 2009;28(2):135-43. doi: 10.1159/000227282. Epub 2009 Jul 4.
7
High-volume hemofiltration in sepsis and SIRS: current concepts and future prospects.脓毒症和全身炎症反应综合征中的高容量血液滤过:当前概念与未来展望。
Blood Purif. 2009;28(1):1-11. doi: 10.1159/000210031. Epub 2009 Mar 27.
8
Dialysis dose in acute kidney injury: no time for therapeutic nihilism--a critical appraisal of the Acute Renal Failure Trial Network study.急性肾损伤中的透析剂量:没时间搞治疗虚无主义——对急性肾衰竭试验网络研究的批判性评价
Crit Care. 2008;12(5):308. doi: 10.1186/cc7016. Epub 2008 Oct 16.
9
Septic acute kidney injury: new concepts.脓毒症急性肾损伤:新概念
Nephron Exp Nephrol. 2008;109(4):e95-100. doi: 10.1159/000142933. Epub 2008 Sep 18.
10
Intensity of renal support in critically ill patients with acute kidney injury.急性肾损伤危重症患者的肾脏支持强度
N Engl J Med. 2008 Jul 3;359(1):7-20. doi: 10.1056/NEJMoa0802639. Epub 2008 May 20.