Leiden University.
J Cogn Neurosci. 2011 Mar;23(3):524-39. doi: 10.1162/jocn.2009.21380. Epub 2009 Nov 19.
The ability to interact with a constantly changing environment requires a balance between maintaining the currently relevant working memory content and being sensitive to potentially relevant new information that should be given priority access to working memory. Mesocortical dopamine projections to frontal brain areas modulate working memory maintenance and flexibility. Recent neurocognitive and neurocomputational work suggests that dopamine release is transiently enhanced by induced positive affect. This ERP study investigated the role of positive affect in different aspects of information processing: in proactive control (context maintenance and updating), reactive control (flexible adaptation to incoming task-relevant information), and evaluative control in an AX-CPT task. Subjects responded to a target probe if it was preceded by a specific cue. Induced positive affect influenced the reactive and evaluative components of control (indexed by the N2 elicited by the target and by the error-related negativity elicited after incorrect responses, respectively), whereas cue-induced proactive preparation and maintenance processes remained largely unaffected (as reflected in the P3b and the contingent negative variation components of the ERP).
与不断变化的环境交互的能力需要在保持当前相关工作记忆内容和对应该优先访问工作记忆的潜在相关新信息的敏感性之间取得平衡。中脑皮质多巴胺投射到额叶脑区调节工作记忆的维持和灵活性。最近的神经认知和神经计算研究表明，多巴胺释放会被诱导的积极情绪短暂增强。这项 ERP 研究调查了积极情绪在信息处理的不同方面的作用：在主动控制（上下文的维持和更新）、反应控制（灵活适应传入的与任务相关的信息）和 AX-CPT 任务中的评价控制。如果目标探针之前有特定的提示，受试者就会做出反应。诱发的积极情绪影响了控制的反应和评价成分（由目标诱发的 N2 和错误反应后诱发的错误相关负波分别表示），而提示诱发的主动准备和维持过程基本不受影响（如 ERP 的 P3b 和伴随的负变成分所示）。
