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从密蒙花茎中分离得到的 5 个新的 C21 甾体糖苷。

Five new C21 steroidal glycosides from the stems of Marsdenia tenacissima.

机构信息

Jiangsu Simcere Pharmaceutical R&D Co., Ltd., No. 699-18 Xuanwu Avenue, Xuanwu District, Nanjing 210042, PR China. jacal

出版信息

Steroids. 2010 Feb;75(2):176-83. doi: 10.1016/j.steroids.2009.11.003. Epub 2009 Nov 17.

DOI:10.1016/j.steroids.2009.11.003
PMID:19925814
Abstract

Five new C(21) steroidal glycosides (1-5) were isolated from the stems of Marsdenia tenacissima. The chemical structures and relative configurations of the new compounds were elucidated by mass spectrometry and NMR spectroscopy. Cellular assay of these compounds showed that they are weak cytotoxic to various cell lines.

摘要

从马兜铃科植物马兜铃的茎中分离得到五个新的 C(21)甾体糖苷 (1-5)。通过质谱和 NMR 光谱解析了这些新化合物的化学结构和相对构型。这些化合物的细胞测定表明它们对各种细胞系具有较弱的细胞毒性。

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