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甲型肝炎和戊型肝炎:预防和流行病学的最新进展。

Hepatitis A and E: update on prevention and epidemiology.

机构信息

World Health Organization, Via Appia 20, CH-1211 Geneva, Switzerland.

出版信息

Vaccine. 2010 Jan 8;28(3):583-8. doi: 10.1016/j.vaccine.2009.10.136. Epub 2009 Nov 17.

DOI:10.1016/j.vaccine.2009.10.136
PMID:19925903
Abstract

In March 2009 the Viral Hepatitis Prevention Board (VHPB) organized a meeting in Antwerp, in order to review the status of epidemiology and prevention of both hepatitis A and E. International hepatitis experts from the public health and academic sector provided the state of the art on HAV and emphasized the growing public health importance of the disease, in particular in intermediate endemicity regions, and the need for control at global level. The information shared on HEV showed clearly that it is emerging, but still a lot of efforts are needed to clarify among others the transmission routes, the clinical presentations and the burden of disease. First data on hepatitis E vaccines were discussed, showing a promising safety and efficacy profile. The meeting was concluded with lessons learnt, challenges, needs and proposed step forwards for both diseases.

摘要

2009 年 3 月,病毒性肝炎预防委员会(VHPB)在安特卫普组织了一次会议,以审查甲型和戊型肝炎的流行病学和预防现状。公共卫生和学术领域的国际肝炎专家介绍了甲型肝炎的最新情况,并强调了该病在特定地区的重要性日益增加,以及在全球范围内进行控制的必要性。有关戊型肝炎的信息表明,戊型肝炎正在出现,但仍需要做出许多努力来明确传播途径、临床表现和疾病负担等问题。会上还讨论了戊型肝炎疫苗的初步数据,结果显示其具有良好的安全性和有效性。会议总结了经验教训、挑战、需求以及针对这两种疾病提出的未来计划。

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